Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p231 | (1) | WCRB2014

Knocking-down detrimental seminal protein PDC-109 minimizes cryoinjury to bull spermatozoa

Srivastava N , Srivastava S K , Ghosh S K , Kumar Amit , Andonissamy J , Ponraj Perumal

Introduction: Seminal PDC-109, most abundant protein in bulls, destabilizes sperm membrane by causing efflux of cholesterol. This detrimental effect is minimized to some extent by addition of egg yolk (EY) in extender. Knocking-down of free floating PDC-109 protein by antibodies (Ab) can be another method not yet reported. Therefore, a study was designed to assess the effect of antibodies-mediated sequestration of PDC-109 protein as compared to EY on minimization of cryoinjury...